When Larsen Bervoets was invited by the city to make a nice mural, he thought it was to obvious to design something about shipping, prostituees (Redlight District is just around the corner) or sailors. He was looking for a strong image. 
One day during a course at the MAS (Museum nearby) he heard a story about Brabo and the Giant Druon Antigone. He inspired his work on the story of a gigantic whale bone which was found in the Middle Ages, in that time nobody knew of the existence of whales. Hence the origin story of the name Antwerp and the Giant Druon. 
The artist worked 10 days on this piece in cold circumstances, but it's still one of the most powerful walls in town.