This mural was part of the 2016 Vancouver Mural Festival. According to the event's website, it represents the Buddhist figures Yama & Mara. The three heads represent Mara's three daughters -- craving, aversion, and desire. The artist (Paige Bowman) also thanks "The Wolf Pak" on the work.
More info on the artist's Instagram (@birdfingersss)
Hunted by Mural Hunter. Pictures by Mural Hunter, Leo.